8.20.2004

Proton Particles Beat Radiation for Tumor

Proton Particles Beat Radiation for Tumor

LOMA LINDA, Calif., Aug 18, 2004 (United Press International via COMTEX) -- California physicians using proton beam therapy to treat cancer patients say the new technique is much better than standard radiation.
"We can radiate, for example, around the eye, and treat a tumor very close to the eye, and have no effect on the eye," said Dr. James Cox, head of radiation oncology at the University of Texas M.D. Anderson Cancer Center.
[feedsfarm.com Search: cancer]
ABC News reported Wednesday

Feet, ankles just as prone to skin cancer (8/20/2004)

Feet, ankles just as prone to skin cancer (8/20/2004)

It's been a great few months for wearing as little footwear as possible. But do you slather sun cream on your feet? Probably not. So it can be a shock to learn that the foot and ankle are as prone to skin cancer as any other part of the body.
[feedsfarm.com Search: cancer]

2003 study published in the Journal of Foot & Ankle Surgery

8.19.2004

Race a Factor in Breast Reconstruction After Mastectomy

Race a Factor in Breast Reconstruction After Mastectomy

African-American women are less likely to be treated with breast reconstruction after mastectomy than women of other races, independent of age and clinical and socioeconomic factors... click link for more info.
[Medical News Today]

August 23, 2004 in the online edition of CANCER

Mammography Has Low Risk of Recall for False Positive Findings

Mammography Has Low Risk of Recall for False Positive Findings

A new long-term study finds over 20 years, only one in five women who have mammograms every two years will have to undergo follow up evaluation for a false positive finding... click link for more info.
[Medical News Today]

August 23, 2004 in the online edition of CANCE

8.18.2004

Dr Sun's soup, a new herbal remedy in the fight against cancer

Dr Sun's soup, a new herbal remedy in the fight against cancer

AsiaNews.IT Aug 18 2004 7:27PM GMT
[feedsfarm.com Search: cancer]


Dr Sun’s herbal remedy is now in its clinical trial phase in the US. If it is approved by the US Federal Food and Drug Administration it could be on sale as a drug by the end of next year. For the time being it is sold freeze-dried in small bags as a dietary supplement.

The soup mix consists of a blend of soy beans, shiitake mushrooms, ginger, ginseng, mung beans, olive, liquorice, leeks, parsley and hawthorn fruit.

American Cancer Society writing free PDA reference

American Cancer Society writing free PDA reference

infoSync Aug 18 2004 10:51PM GMT
[feedsfarm.com Search: cancer]

Lung cancer different in nonsmokers

Lung cancer different in nonsmokers

Among individuals who develop lung cancer, there appear to be differences between smokers and nonsmokers in survival rates and in individuals patient characteristics, researchers report. They say the findings indicate that lung cancer in nonsmokers is a specific disease, which has implications for research and clinical trials.

Dr. George R. Simon and colleagues from the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida, analyzed patient characteristics and survival...
[feedsfarm.com Search: cancer]

SOURCE: Chest, August 2004

Health News Article Blood Test Better Predicts Cancer Treatment Outcomes- Reuters.com: " A new technology that counts cancer cells in the blood helps predict the success of breast cancer treatments more quickly and more reliably than established methods researchers reported on Wednesday. A study published in Thursday's edition of The New England Journal of Medicine said the new technique allows doctors to determine within weeks not months whether a breast cancer patient's treatment is working. "

Sweet success in targeting sugar molecules to cells in living animals: "Howard Hughes Medical Institute researchers have successfully targeted unnatural sugar molecules with chemically unique functional groups onto the surfaces of cells in living animals without altering the animals%27 physiology. %0D%0AThe achievement is a significant advance in the promising new field of metabolic engineering because it provides a new tool with which researchers can label specific cells in whole animals so that they can differentiate one cell from another. " August 19, 2004, issue of the journal Nature

Intervention studies that use cancer patients from high-risk clinics may be subject to bias: "Many studies have tried to evaluate the effects of interventions to reduce cancer risk%2C such as tamoxifen therapy or prophylactic surgery%2C among patients that carry a mutation that increases their risk of cancer. However%2C some of the studies that use subjects from clinics that care for people at high risk of the disease may be subject to serious selection bias%2C according to a commentary that appears in the August 18 issue of the Journal of the National Cancer Institute. "

Personal WeblogRoger Bennett%27s Midnight Meditations%3A Quick Update from Houston: "Debbie and I are back at MD Anderson today for my weekly follow-up. They are still treating the blood infection with mega doses of %22goop.%22 %28I like to use medical jargon%29 I%27m feeling fine and am hoping my appointment in about an hour from now will give me good news."

80% of cancer patients use some form of complementary or alternative therapies

80% of cancer patients use some form of complementary or alternative therapies

news-medical.net - Aug 18 2004 16:49:47 GMT
[All Headline News - News and Headlines]
http://www.cancer.org

Exposure to natural and man-made substances in the environment accounts for at least two-thirds of all the cases of cancer in the U.S.

Exposure to natural and man-made substances in the environment accounts for at least two-thirds of all the cases of cancer in the U.S.

news-medical.net - Aug 18 2004 16:49:47 GMT
[All Headline News - News and Headlines]

http://www.nci.nih.gov

8.17.2004

Advanced Renal Cell Carcinoma drug, Temsirolimus, gets fast track...

Advanced Renal Cell Carcinoma drug, Temsirolimus, gets fast track...

Current available therapy for patients with metastatic RCC is immunotherapy with cytokines, which provides a tumor response (shrinkage) in some patients.
[Cancer - Topix.net]

Study: Hormones help prostate cancer survival

Study: Hormones help prostate cancer survival

cnn.com - Aug 18 2004 2:7:44 GMT
[All Headline News - News and Headlines]

Almost five years after treatment, six men in the radiation-only study group died of prostate cancer; none of the men who got combined treatment died of prostate cancer. The study involved about 200 men.
The study by researchers at Boston's Brigham and Women's Hospital and Dana Farber Cancer Institute appears in Wednesday's Journal of the American Medical Association.
In a JAMA editorial, Dr. Thomas DeWeese of Johns Hopkins University, said the study did not address how the drug treatment affected patients' quality of life. He also said the radiation dose was lower than is frequently given, which might explain the differing survival rates.

Gene Variant Linked to Prostate Cancer Risk

Gene Variant Linked to Prostate Cancer Risk

news.yahoo.com - Aug 18 2004 1:53:29 GMT
[All Headline News - News and Headlines]
"Inflammation in the prostate may go unchecked in carriers with this (variant), leading to an increased risk for tumor development," Dr. Henrik Gronberg and colleagues report in the Journal of the National Cancer Institute

MICs shed light on prostate cancer:Prevalent expression of the immunostimulatory MHC class I chain–related molecule is counteracted by shedding in prostate cancer "Jennifer Wu and colleagues%2C at the University of Washington%2C now investigate how prostate cancers evade this anti-tumor defense strategy. The researchers found that MIC-expressing prostate cancer cell lines were able to activate natural killer cells%2C thus%2C initially%2C this defense mechanism appeared intact. Analysis of prostate tumor biopsies showed that the cell surface localization of MIC was highest in early-stage tumors. The researchers noted that tumors from later-stage patients%2C however%2C could no longer activate natural killer cells%2C and that there were high levels soluble MIC in the blood serum of these patients. "

Decreased Breast Cancer Tumor Size%2C Stage%2C and Mortality in: "Background%3A Since the 1980s%2C Rhode Island has achieved one of the highest mammography screening rates in the nation. The objective of this study was to determine the effect of high mammography rates on breast cancer presentation and outcomes.%0D%0AMethods%3A Using the Rhode Island Cancer Registry%2C the incidence of DCIS and invasive cancer%2C tumor size%2C stage%2C rate of BCS and mortality from breast cancer were determined from 1987 to 2001. %0D%0AResults%3A Over 80%25 of Rhode Island women report routine mammography. From 1987 to 2001%2C there were 1%2C660 cases of DCIS and 11%2C301 cases of invasive breast cancer. Although the overall incidence of invasive cancer was stable%2C the median diameter decreased from 2 cm to 1.5 cm with a significant decrease in the incidence of stage III and IV cancers. There was an increase in BCS for women 50 to 64 years of age with stage I and II disease and for women older than 65 years with stage I disease. Disease-specific mortality decreased by 25%25.%0D%0AConclusions%3A High mammography rates in Rhode Island are associated with smaller and earlier-stage breast cancers. This largely accounts for the decreased mortality from breast cancer and the increased rate of BCS."

Breast cancer screening underutilized by ethnic women

Breast cancer screening underutilized by ethnic women

Lack of information, modesty and a false sense of security may prevent women from immigrant backgrounds from having regular clinical breast examinations, says a study by the University of Toronto and the University Health Network (UHN)... click link for more info.
[Medical News Today]

Enhancing stem cell transplants

Enhancing stem cell transplants

Inhibition of peptidase CD26 found to increase efficiency of procedure in mice
[News from The Scientist]

Joining Forces to Combat Multiple Myeloma

Joining Forces to Combat Multiple Myeloma

After years of working toward the same goal as rivals, four leading cancer centers are linking efforts to fight a deadly bone disease.
[Cancer - Topix.net]

addtional:
The plan, a rare break from tradition for competing academic centers, is designed to focus attention and funding on multiple myeloma, a blood cancer that erodes the bones and kills quickly. About 46,000 Americans have the disease, though they make up only a small portion of the total cancer population. As a result, experts say, research is limited and drug companies are slow to develop treatments.

Joining Forces to Combat Multiple Myeloma By ANAHAD O'CONNORPublished: August 17, 2004 NYT


Are physicians over-performing colonoscopy?

Are physicians over-performing colonoscopy?

Many physicians appear to be performing more "surveillance" colonoscopies than expert groups deem necessary, according to results of a National Cancer Institute-funded study published in the Aug.
[Cancer - Topix.net]

Molecule Stops Cancer Tumor Growth

Molecule Stops Cancer Tumor Growth

ATLANTA, Aug 13, 2004 (United Press International via COMTEX) -- U.S. scientists have solved the structural puzzle of how an emerging class of promising cancer drugs work to halt cell division.
[Cancer - Topix.net]

8.16.2004

The New York Times > Business > Heart Ailment Warning on Cancer Drug: "The government and Genentech are warning doctors that Avastin, which is used to treat colorectal cancer, increases patients' risk of chest pain, strokes, ministrokes, heart attacks and potentially lethal heart ailments."

ASCO releases new colon cancer guideline: "The guideline, published in the August 15 issue of the Journal of Clinical Oncology, states that the routine use of adjuvant chemotherapy for medically fit, average-risk patients with Stage II colon cancer is not recommended. Clinical trials have not established with certainty a significant degree of clinical benefit for adjuvant chemotherapy in patients with Stage II colon cancer, although most trials show a small benefit from adjuvant chemotherapy. "

Immune vaccine followed by chemotherapy slows incurable brain tumors, lengthens survival: " Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have found that the combination of immunotherapy and chemotherapy significantly slowed tumor progression and extended survival of patients with glioblastoma multiforme (GBM), extremely aggressive and incurable brain tumors.
Although the exact mechanism is yet to be identified, the research team theorizes that like a one-two punch, the anti-tumor vaccine delivers an initial blow to the tumor cells which increases their vulnerability to tumor-killing drugs" August 15, 2004 Clinical Cancer Research


Ovarian cancer sheds tumor suppression with loss of estrogen receptor: "An important receptor for estrogen in ovarian cells has been shown to suppress tumor growth, according to a new study published in the August 15 issue of the journal Cancer Research. When ovarian tumors develop, however, the number of these receptors--known as estrogen receptor beta (ER beta)--diminishes, encouraging these tumors to advance toward malignancy and metastasis. This disappearing act may help explain why ovarian cancers are often typically resistant to anti-estrogen drugs including Tamoxifen. "

Marijuana ingredient inhibits VEGF pathway required for brain tumor blood vessels: "Cannabinoids, the active ingredients in marijuana, restrict the sprouting of blood vessels to brain tumors by inhibiting the expression of genes needed for the production of vascular endothelial growth factor (VEGF).
According to a new study published in the August 15, 2004 issue of the journal Cancer Research, administration of cannabinoids significantly lowered VEGF activity in laboratory mice and two patients with late-stage glioblastoma. "

Hopkins scientists use blood proteins to detect ovarian cancer: "Johns Hopkins Kimmel Cancer Center researchers have designed a blood test to detect ovarian cancer using three proteins found in common in the blood of women with the disease. Their preliminary studies with the new test suggest a molecular signature exclusive to this deadly cancer, known for its ability to remain undetected and spread quickly. "

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